Wwox Deletion in Mouse B Cells Leads to Genomic Instability, Neoplastic Transformation, and Monoclonal Gammopathies

Author:

McBride Kevin M.,Kil Hyunsuk,Mu Yunxiang,Plummer Joshua B.,Lee Jaeho,Zelazowski Maciej J.,Sebastian Manu,Abba Martin C.,Aldaz C. Marcelo

Publisher

Frontiers Media SA

Subject

Cancer Research,Oncology

Reference61 articles.

1. WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3–24.1, a region frequently affected in breast cancer;Bednarek;Cancer Res,2000

2. Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells;Ried;Hum Mol Genet,2000

3. The common fragile site FRA16D and its associated gene WWOX are highly conserved in the mouse at Fra8E1;Krummel;Genes Chromosomes Cancer,2002

4. WWOX, the FRA16D gene, behaves as a suppressor of tumor growth;Bednarek;Cancer Res,2001

5. Signatures of mutation and selection in the cancer genome;Bignell;Nature,2010

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