Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis-Reference-Cited by-同舟云学术

Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis

Published:2015-05-08 Issue: Volume:9 Page:
ISSN:1662-5153
Container-title:Frontiers in Behavioral Neuroscience
language:
Short-container-title:Front. Behav. Neurosci.

Author:

Impellizzeri Agata Antonina Rita,Pappalardo Matteo,Basile Livia,Manfra Ornella,Andressen Kjetil Wessel,Krobert Kurt Allen,Messina Angela,Levy Finn Olav,Guccione Salvatore

Publisher

Frontiers Media SA

Subject

Behavioral Neuroscience,Cognitive Neuroscience,Neuropsychology and Physiological Psychology

Reference33 articles.

1. Biased probability Monte Carlo conformational searches and electrostatic calculations for peptides and proteins;Abagyan;J. Mol. Biol.,1994

2. Activation of the Î²2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6;Ballesteros;J. Biol. Chem.,2001

3. Integrated methods for modeling G-protein coupled receptors;Ballesteros;Methods Neurosci.,1995

4. Molecular dynamics with coupling to an external bath;Berendsen;J. Chem. Phys.,1984

5. Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor;Boess;J. Neurochem.,1998

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, Synthesis and Biological Evaluation of Novel 1,3,5-Triazines: Effect of Aromatic Ring Decoration on Affinity to 5-HT7 Receptor;International Journal of Molecular Sciences;2022-11-01

2. Design and synthesis of new potent 5-HT7 receptor ligands as a candidate for the treatment of central nervous system diseases;European Journal of Medicinal Chemistry;2022-01

3. Low Basicity as a Characteristic for Atypical Ligands of Serotonin Receptor 5-HT2;International Journal of Molecular Sciences;2021-01-21

4. The relationship between stereochemical and both, pharmacological and ADME-Tox, properties of the potent hydantoin 5-HT7R antagonist MF-8;Bioorganic Chemistry;2021-01

5. International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function;Pharmacological Reviews;2020-12-22