Author:
Ramachandran Prasanna Venkatesh,Healy C. Mary,Lambert Elton M.,Guerra Deyanara,Curry Choladda V.,Vogel Tiphanie P.
Abstract
Elevated immunoglobulin E (IgE) levels can be associated with infectious, allergic and inflammatory disorders, and rarely as a manifestation of an inborn error of immunity. Here we report the case of an adolescent female who presented with a gradually enlarging neck mass, lymphadenopathy, eosinophilia and highly elevated IgE levels. Laboratory and histopathologic evaluation revealed an unlikely diagnosis of Kimura Disease. We discuss the differential diagnosis of a neck mass with prominent eosinophils on histology, and review support for T-helper type 2 (Th2) cell activation and hyper-IgE in Kimura Disease.
Subject
Pediatrics, Perinatology, and Child Health
Reference29 articles.
1. On the unusual granulation combined with hyperplastic changes of lymphatic tissue;Kimura;Trans Soc Pathol Jpn.,1948
2. Kimura disease: CT and MR imaging findings;Park;Am J Neuroradiol.,2012
3. Kimura's disease of the parotid region: report of 2 cases and review of the literature;Meningaud;J Oral Maxillofac Surg.,2007
4. Kimura disease: no age or ethnicity limit;AlGhamdi;Saudi Med J.,2016
5. Kimura disease: a clinicopathologic study of 21 cases;Chen;Am J Surg Pathol.,2004
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