Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein
Author:
Funder
National Institutes of Health
Publisher
Frontiers Media SA
Subject
Genetics (clinical),Genetics,Molecular Medicine
Reference16 articles.
1. SARS-CoV-2 strategically mimics proteolytic activation of human ENaC.;Anand;eLife,2020
2. The proximal origin of SARS-CoV-2.;Andersen;Nat. Med.,2020
3. A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3.;Cingolani;Fly,2012
4. The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade.;Coutard;Antiviral Res.,2020
5. Characterisation of the transcriptome and proteome of SARS-CoV-2 using direct RNA sequencing and tandem mass spectrometry reveals evidence for a cell passage induced in-frame deletion in the spike glycoprotein that removes the furin-like cleavage site.;Davidson;bioRxiv [Preprint],2020
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