Pharmacogenomics of acetaminophen in pediatric populations: a moving target

Author:

Krasniak Anne E.,Knipp Gregory T.,Svensson Craig K.,Liu Wanqing

Publisher

Frontiers Media SA

Subject

Genetics(clinical),Genetics,Molecular Medicine

Reference61 articles.

1. Analgesic efficacy of paracetamol in children using tonsillectomy as a pain model.;Anderson;Anaesth. Intensive Care,1996

2. The CYP2E1-humanized transgenic mouse: role of CYP2E1 in acetaminophen toxicity.;Cheung;Drug Metab. Dispos.,2005

3. Interindividual variability in acetaminophen glucuronidation by human liver microsomes, identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms.;Court;J. Pharmacol. Exp. Ther.,2001

4. The UDP-Glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A Exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen-induced acute liver failure;Court;J. Pharmacol. Exp. Ther.,2013

5. Candidate gene polymorphisms in patients with acetaminophen-induced acute liver failure.;Court;Drug Metab. Dispos.,2014

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