Metformin Ameliorates Gestational Diabetes Mellitus-Induced Endothelial Dysfunction via Downregulation of p65 and Upregulation of Nrf2-Reference-Cited by-同舟云学术

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Metformin Ameliorates Gestational Diabetes Mellitus-Induced Endothelial Dysfunction via Downregulation of p65 and Upregulation of Nrf2

Published:2020-10-09 Issue: Volume:11 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Sun Cong Cong,Lai Ya Nan,Wang Wen Huan,Xu Xiao Min,Li Xiao Qing,Wang Hai,Zheng Jia Yong,Zheng Jian Qiong

Funder

Natural Science Foundation of Zhejiang Province

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference61 articles.

1. Chicoric acid prevents methotrexate-induced kidney injury by suppressing NF-κB/NLRP3 inflammasome activation and up-regulating Nrf2/ARE/HO-1 signaling;Abd El-Twab;Inflammation Res.,2019

2. Gestational Diabetes alters functions in offspring’s umbilical cord cells with implications for cardiovascular health;Amrithraj;Endocrinology,2017

3. Glibenclamide, metformin, and insulin for the treatment of gestational diabetes: a systematic review and meta-analysis;Balsells;BMJ,2015

4. Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases;Barnes;N Engl. J. Med.,1997

5. Metformin in overweight and obese women with gestational diabetes: a propensity score-matched study;Bettencourt-Silva;Endocrine,2019

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1. Mitigation of gestational diabetes-induced endothelial dysfunction through FGF21-NRF2 pathway activation involving L-Cystine;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2024-10

2. Crosstalk between inflammasomes, inflammation, and Nrf2: Implications for gestational diabetes mellitus pathogenesis and therapeutics;European Journal of Pharmacology;2024-01

3. Combination therapy of metformin and atorvastatin against benzopyrene-induced lung cancer via inflammatory signaling pathway;General physiology and biophysics;2024

4. INVESTIGATION OF THE EFFECTS OF METFORMIN ON THE miR-21/PTEN/Akt PATHWAY IN HT-29 HUMAN COLORECTAL ADENOCARCINOMA CELL AND HUVEC CO-CULTURE;FARMACIA;2024

5. The Role of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) in Pathological Pregnancy;Hans Journal of Biomedicine;2024

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