Aldo–Keto Reductase AKR1C1–AKR1C4: Functions, Regulation, and Intervention for Anti-cancer Therapy-Reference-Cited by-同舟云学术

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Aldo–Keto Reductase AKR1C1–AKR1C4: Functions, Regulation, and Intervention for Anti-cancer Therapy

Published:2017-03-14 Issue: Volume:8 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Zeng Chen-Ming,Chang Lin-Lin,Ying Mei-Dan,Cao Ji,He Qiao-Jun,Zhu Hong,Yang Bo

Funder

National Natural Science Foundation of China

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference90 articles.

1. Discovery of substituted 3-(phenylamino)benzoic acids as potent and selective inhibitors of type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3).;Adeniji;Bioorg. Med. Chem. Lett.,2011

2. Intrauterine infection and preterm labor.;Agrawal;Paper Presented at: Seminars in Fetal and Neonatal Medicine.,2012

3. The aldo-keto reductase superfamily and its role in drug metabolism and detoxification.;Barski;Drug Metab. Rev.,2008

4. Development of nonsteroidal anti-inflammatory drug analogs and steroid carboxylates selective for human aldo-keto reductase isoforms: potential antineoplastic agents that work independently of cyclooxygenase isozymes.;Bauman;Mol. Pharmacol.,2005

5. Progestins as inhibitors of the human 20-ketosteroid reductases, AKR1C1 and AKR1C3.;Beranic;Chem. Biol. Interact,2011

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1. AKR1C3 promotes progression and mediates therapeutic resistance by inducing epithelial-mesenchymal transition and angiogenesis in small cell lung cancer;Translational Oncology;2024-09

2. AKR1C1 interacts with STAT3 to increase intracellular glutathione and confers resistance to oxaliplatin in colorectal cancer;Acta Pharmaceutica Sinica B;2024-09

3. Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway;Cell Chemical Biology;2024-08

4. AI Based Discovery of a New AKR1C3 Inhibitor for Anticancer Applications;ACS Medicinal Chemistry Letters;2024-07-03

5. AKR1C4 regulates the sensitivity of colorectal cancer cells to chemotherapy through ferroptosis modulation;Cancer Chemotherapy and Pharmacology;2024-06-18

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