The P2Y12 Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4-/- Mouse Model of Retinal Degeneration-Reference-Cited by-同舟云学术

The P2Y12 Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4-/- Mouse Model of Retinal Degeneration

Published:2018-04-19 Issue: Volume:9 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Lu Wennan,Gómez Néstor M.,Lim Jason C.,Guha Sonia,O’Brien-Jenkins Ann,Coffey Erin E.,Campagno Keith E.,McCaughey Stuart A.,Laties Alan M.,Carlsson Leif G.,Mitchell Claire H.

Funder

National Eye Institute

AstraZeneca

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference45 articles.

1. The P2X7 receptor primes IL-1β and the NLRP3 inflammasome in astrocytes exposed to mechanical strain.;Albalawi;Front. Cell. Neurosci.,2017

2. Characterization of the adenosine pharmacology of ticagrelor reveals therapeutically relevant inhibition of equilibrative nucleoside transporter 1.;Armstrong;J. Cardiovasc. Pharmacol. Ther.,2014

3. Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor.;Aungraheeta;Blood,2016

4. Acidic nanoparticles restore lysosomal pH and degradative function in compromised RPE cells.;Baltazar;PLoS One,2012

5. Antiplatelet therapy in acute coronary syndromes: focus on ticagrelor.;Birkeland;J. Blood Med.,2010

Cited by 18 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Impaired cathepsin D in retinal pigment epithelium cells mediates Stargardt disease pathogenesis;The FASEB Journal;2024-06-05

2. Exploring role of natural compounds in molecular alterations associated with brain ageing: A perspective towards nutrition for ageing brain;Ageing Research Reviews;2024-06

3. Recent Advances in Our Understanding of Age-Related Macular Degeneration: Mitochondrial Dysfunction, Redox Signaling, and the Complement System;aging and disease;2024

4. Lipofuscin, Its Origin, Properties, and Contribution to Retinal Fluorescence as a Potential Biomarker of Oxidative Damage to the Retina;Antioxidants;2023-12-13

5. Cell-autonomous lipid-handling defects in Stargardt iPSC-derived retinal pigment epithelium cells;Stem Cell Reports;2022-11