DPD Testing Before Treatment With Fluoropyrimidines in the Amsterdam UMCs: An Evaluation of Current Pharmacogenetic Practice

Author:

Martens Forike K.,Huntjens Daan W.,Rigter Tessel,Bartels Meike,Bet Pierre M.,Cornel Martina C.

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference16 articles.

1. Dihydropyrimidine dehydrogenase gene variation and severe 5-fluorouracil toxicity: a haplotype assessment;Amstutz;Pharmacogenomics,2009

2. Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity;Amstutz;Pharmacogenomics,2011

3. Safety, pharmacokinetics (PK), and cost-effectiveness of upfront genotyping of DPYD in fluoropyrimidine therapy;Deenen;J. Clin. Oncol.,2011

4. Prevention of severe toxicity from capecitabine, 5-fluorouracil and tegafur by screening for DPD-deficiency;Deenen;Ned. tijdschr. voor geneeskd.,2012

5. Upfront genotyping of DPYD*2A to individualize fluoropyrimidine therapy: A Safety and Cost Analysis;Deenen;J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol.,2016

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