Exposure of Infants to Isoniazid via Breast Milk After Maternal Drug Intake of Recommended Doses Is Clinically Insignificant Irrespective of Metaboliser Status. A Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach to Estimate Drug Exposure of Infants via Breast-Feeding-Reference-Cited by-同舟云学术

Exposure of Infants to Isoniazid via Breast Milk After Maternal Drug Intake of Recommended Doses Is Clinically Insignificant Irrespective of Metaboliser Status. A Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach to Estimate Drug Exposure of Infants via Breast-Feeding

Published:2019-01-22 Issue: Volume:10 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Garessus Estella Dora Germaine,Mielke Hans,Gundert-Remy Ursula

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference53 articles.

1. Tuberculosis and tuberculosis/HIV co-infection in pregnancy.;Adhikari;Semin. Fetal Neonatal Med.,2009

2. Modeling drug passage into human milk.;Anderson;Clin. Pharmacol. Ther.,2016

3. The sodium, potassium, and water contents of red blood cells of healthy human adults.;Beiling;J. Clin. Invest.,1966

4. Isoniazid and acetylisoniazid disposition in human milk, saliva and plasma.;Berlin;Fed. Proc.,1979

5. Enzymatic inactivation of isonicotinic acid hydrazide in human and animal organism.;Bonicke;Archiv für Experimentelle Pathologie und Pharmakologie,1953

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study;Wellcome Open Research;2024-08-12

2. Pharmacokinetics of drugs used to treat drug sensitive-tuberculosis in breastfeeding mother-infant pairs: An observational pharmacokinetic study;Wellcome Open Research;2024-05-21

3. Determining the exposure of maternal medicines through breastfeeding: the UmbrelLACT study protocol—a contribution from the ConcePTION project;BMJ Paediatrics Open;2024-04

4. Systematic review of physiologically based kinetic lactation models for transfer of xenobiotic compounds to milk;Toxicology and Applied Pharmacology;2023-05

5. Infant Exposure to Antituberculosis Drugs via Breast Milk and Assessment of Potential Adverse Effects in Breastfed Infants: Critical Review of Data;Pharmaceutics;2023-04-13