In Silico Assessment of Efficacy and Safety of IKur Inhibitors in Chronic Atrial Fibrillation: Role of Kinetics and State-Dependence of Drug Binding-Reference-Cited by-同舟云学术

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In Silico Assessment of Efficacy and Safety of IKur Inhibitors in Chronic Atrial Fibrillation: Role of Kinetics and State-Dependence of Drug Binding

Published:2017-11-07 Issue: Volume:8 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Ellinwood Nicholas,Dobrev Dobromir,Morotti Stefano,Grandi Eleonora

Funder

National Institutes of Health

American Heart Association

Heart Rhythm Society

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference57 articles.

1. Rate-dependent role of IKur in human atrial repolarization and atrial fibrillation maintenance;Aguilar;Biophys. J.,2017

2. Differences between outward currents of human atrial, and subepicardial ventricular myocytes;Amos;J. Physiol.,1996

3. The clinical profile and pathophysiology of atrial fibrillation: relationships among clinical features, epidemiology, and mechanisms. Circ;Andrade;Res.,2014

4. Human atrial fibrillation: insights from computational electrophysiological models. Trends Cardiovasc;Bers;Med.,2011

5. Ionic mechanisms of electrical remodeling in human atrial fibrillation;Bosch;Cardiovasc. Res.,1999

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