Impact of Subacute Exposure to T-2 Toxin and Zearalenone on the Pharmacokinetics of Midazolam as CYP3A Probe Drug in a Porcine Animal Model: A Pilot Study-Reference-Cited by-同舟云学术

Impact of Subacute Exposure to T-2 Toxin and Zearalenone on the Pharmacokinetics of Midazolam as CYP3A Probe Drug in a Porcine Animal Model: A Pilot Study

Published:2019-04-16 Issue: Volume:10 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Schelstraete Wim,Devreese Mathias,Croubels Siska

Funder

Bijzonder Onderzoeksfonds

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference52 articles.

1. Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers.;Abel;Br. J. Clin. Pharmacol.,2008

2. Impact of Fusarium mycotoxins on hepatic and intestinal mRNA expression of cytochrome P450 enzymes and drug transporters, and on the pharmacokinetics of oral enro fl oxacin in broiler chickens.;Antonissen;Food Chem. Toxicol.,2017

3. Zearalenone activates pregnane X receptor, constitutive androstane receptor and aryl hydrocarbon receptor and corresponding phase I target genes mRNA in primary cultures of human hepatocytes.;Ayed-Boussema;Environ. Toxicol. Pharmacol.,2010

4. Grapefruit juice – drug interactions.;Bailey;Br. J. Clin. Pharmacol.,1998

5. Pharmacokinetics of the trichothecene mycotoxin, T-2 toxin, in swine and cattle.;Beasley;Toxicon,1986

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