Blinded In Silico Drug Trial Reveals the Minimum Set of Ion Channels for Torsades de Pointes Risk Assessment-Reference-Cited by-同舟云学术

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Blinded In Silico Drug Trial Reveals the Minimum Set of Ion Channels for Torsades de Pointes Risk Assessment

Published:2020-01-30 Issue: Volume:10 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Zhou Xin,Qu Yusheng,Passini Elisa,Bueno-Orovio Alfonso,Liu Yang,Vargas Hugo M.,Rodriguez Blanca

Funder

Wellcome Trust

British Heart Foundation

National Centre for the Replacement Refinement and Reduction of Animals in Research

BHF Centre of Research Excellence, Oxford

Horizon 2020

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference75 articles.

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2. Gender differences in electrophysiological gene expression in failing and non-failing human hearts;Ambrosi;PloS One,2013

3. The M cell: its contribution to the ECG and to normal and abnormal electrical function of the heart;Antzelevitch;J. Cardiovasc. Electrophysiol.,1999

4. Role of transmural dispersion of repolarization in the genesis of drug-induced torsades de pointes;Antzelevitch;Heart Rhythm,2005

5. Multiscale modelling of drug-induced effects on cardiac electrophysiological activity;Brennan;Eur. J. Pharm. Sci.,2009

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