Rhein Derivative 4F Inhibits the Malignant Phenotype of Breast Cancer by Downregulating Rac1 Protein-Reference-Cited by-同舟云学术

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Rhein Derivative 4F Inhibits the Malignant Phenotype of Breast Cancer by Downregulating Rac1 Protein

Published:2020-05-28 Issue: Volume:11 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Li Xinxiao,Liu Yunfeng,Zhao Yuhua,Tian Wei,Zhai Lina,Pang Huifeng,Kang Jiankang,Hou Huaxin,Chen Yanhua,Li Danrong

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangxi Zhuang Autonomous Region

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference39 articles.

1. Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens;Behan;Nature,2019

2. Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease;Bianchini;Nat. Rev. Clin. Oncol.,2016

3. Rac1 GTPase: a “Rac” of all trades;Bosco;Cell Mol. Life Sci.,2009

4. AMP-activated protein kinase: a potential therapeutic target for triple-negative breast cancer;Cao;Breast Cancer Res.,2019

5. Emodin, aloe-emodin and rhein induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells;Chen;Anticancer Res.,2010

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1. Molecular dynamic simulation reveals the inhibiting impact of Rhein on wild-type and P29S-mutated Rac1;Frontiers in Molecular Biosciences;2024-08-05

2. Cellular Traction Force Holds the Potential as a Drug Testing Readout for In Vitro Cancer Metastasis;Cellular and Molecular Bioengineering;2024-06

3. Therapeutic Potential of 1,8-Dihydroanthraquinone Derivatives for Breast Cancer;International Journal of Molecular Sciences;2023-10-31

4. Tetramethylpyrazine-Rhein Derivative inhibits the migration of canine inflammatory mammary carcinoma cells by mitochondrial damage-mediated apoptosis and cadherins downregulation;Biomedicine & Pharmacotherapy;2023-06

5. Dahuang—Taoren, a botanical drug combination, ameliorates adenomyosis via inhibiting Rho GTPases;Frontiers in Pharmacology;2023-03-06

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