Author:
Lu Huiting,Zada Shah,Yang Lingzhi,Dong Haifeng
Abstract
The collection and analysis of biological samples are an effective means of disease diagnosis and treatment. Blood sampling is a traditional approach in biological analysis. However, the blood sampling approach inevitably relies on invasive techniques and is usually performed by a professional. The microneedle (MN)-based devices have gained increasing attention due to their noninvasive manner compared to the traditional blood-based analysis method. In the present review, we introduce the materials for fabrication of MNs. We categorize MN-based devices based on four classes: MNs for transdermal sampling, biomarker capture, detecting or monitoring analytes, and bio-signal recording. Their design strategies and corresponding application are highlighted and discussed in detail. Finally, future perspectives of MN-based devices are discussed.
Funder
National Natural Science Foundation of China
Young Scientists Fund
Beijing Municipal Science and Technology Commission
Subject
Biomedical Engineering,Histology,Bioengineering,Biotechnology
Cited by
17 articles.
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