Author:
Xi Shiwen,Yang Yong-Guang,Suo Jian,Sun Tianmeng
Abstract
Malignant tumors pose a serious threat to human health and have high fatality rates. Conventional clinical anti-tumor treatment is mainly based on traditional surgery, chemotherapy, radiotherapy, and interventional therapy, and even though these treatment methods are constantly updated, a satisfactory efficacy is yet to be obtained. Therefore, research on novel cancer treatments is being actively pursued. We review the classification of gene therapies of malignant tumors and their advantages, as well as the development of gene editing techniques. We further reveal the nano-drug delivery carrier effect in improving the efficiency of gene editing. Finally, we summarize the progress in recent years of gene editing techniques based on nano-drug delivery carriers in the treatment of various malignant tumors, and analyze the prospects of the technique and its restricting factors.
Funder
National Key Research and Development Program of China
National Natural Science Foundation of China
Jilin Scientific and Technological Development Program
First Hospital of Jilin University
Fundamental Research Funds for the Central Universities
Subject
Biomedical Engineering,Histology,Bioengineering,Biotechnology
Cited by
3 articles.
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