Magnetic Microdimer as Mobile Meter for Measuring Plasma Glucose and Lipids

Author:

Yu Shimin,Sun Zhongqi,Zhang Zhanxiang,Sun Haoran,Liu Lina,Wang Wuyi,Li Mu,Zhao Qingsong,Li Tianlong

Abstract

With the development of designed materials and structures, a wide array of micro/nanomachines with versatile functionalities are employed for specific sensing applications. Here, we demonstrated a magnetic propelled microdimer-based point-of-care testing system, which can be used to provide the real-time data of plasma glucose and lipids relying on the motion feedback of mechanical properties. On-demand and programmable speed and direction of the microdimers can be achieved with the judicious adjustment of the external magnetic field, while their velocity and instantaneous postures provide estimation of glucose, cholesterol, and triglycerides concentrations with high temporal accuracy. Numerical simulations reveal the relationship between motility performance and surrounding liquid properties. Such technology presents a point-of-care testing (POCT) approach to adapt to biofluid measurement, which advances the development of microrobotic system in biomedical fields.

Publisher

Frontiers Media SA

Subject

Biomedical Engineering,Histology,Bioengineering,Biotechnology

Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Application of micro/nanorobot in medicine;Frontiers in Bioengineering and Biotechnology;2024-01-25

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3. Micro-/nanoscale robotics for chemical and biological sensing;Lab on a Chip;2023

4. Biocompatible micromotors for biosensing;Analytical and Bioanalytical Chemistry;2022-08-31

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