A Predictive and Preventive Model for Onset of Alzheimer's Disease

Author:

Singhania Udit,Tripathy Balakrushna,Hasan Mohammad Kamrul,Anumbe Noble C.,Alboaneen Dabiah,Ahmed Fatima Rayan Awad,Ahmed Thowiba E.,Nour Manasik M. Mohamed

Abstract

Alzheimer's Disease (AD) is a neurodegenerative irreversible brain disorder that gradually wipes out the memory, thinking skills and eventually the ability to carry out day-to-day tasks. The amount of AD patients is rapidly increasing due to several lifestyle changes that affect biological functions. Detection of AD at its early stages helps in the treatment of patients. In this paper, a predictive and preventive model that uses biomarkers such as the amyloid-beta protein is proposed to detect, predict, and prevent AD onset. A Convolution Neural Network (CNN) based model is developed to predict AD at its early stages. The results obtained proved that the proposed model outperforms the traditional Machine Learning (ML) algorithms such as Logistic Regression, Support Vector Machine, Decision Tree Classifier, and K Nearest Neighbor algorithms.

Funder

Universiti Kebangsaan Malaysia

Publisher

Frontiers Media SA

Subject

Public Health, Environmental and Occupational Health

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Introduction to Predictive Analysis in Healthcare;Advances in Medical Diagnosis, Treatment, and Care;2024-05-30

2. Prediction of Alzheimer’S Disease from Magnetic Resonance Images (MRI);2024 IEEE International Conference on Computing, Power and Communication Technologies (IC2PCT);2024-02-09

3. Dementia Severity Age: A Novel Indicator to Predict the Onset of MCI and Alzheimer's Dementia;2024

4. Lipidomic markers for the prediction of progression from mild cognitive impairment to Alzheimer's disease;The FASEB Journal;2023-06-08

5. Prediction of Dementia Using Deep Learning;Lecture Notes in Networks and Systems;2023

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