Author:
Pontrelli Giuseppe,Cimini Giulio,Roversi Marco,Gabrielli Andrea,Salina Gaetano,Bernardi Stefania,Rocchi Francesca,Simonetti Alessandra,Giaquinto Carlo,Rossi Paolo,Sylos Labini Francesco
Abstract
SARS-CoV-2 is currently causing hundreds of deaths every day in European countries, mostly in not yet vaccinated elderly. Vaccine shortage poses relevant challenges to health authorities, called to act promptly with a scarcity of data. We modeled the mortality reduction of the elderly according to a schedule of mRNA SARS-CoV-2 vaccine that prioritized first dose administration. For the case study of Italy, we show an increase in protected individuals up to 53.4% and a decrease in deaths up to 19.8% in the cohort of over 80's compared with the standard vaccine recalls after 3 or 4 weeks. This model supports the adoption of vaccination campaigns that prioritize the administration of the first doses in the elderly.
Subject
Public Health, Environmental and Occupational Health
Reference25 articles.
1. Vaccinazione anti-SARS-CoV-2/COVID-19 Raccomandazioni ad interim sui gruppi target della vaccinazione anti-SARS-CoV-2/COVID-192021
2. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine;Polack;N Engl J Med,2020
3. Efficacy and safety of the mRNA-1273 SARS-CoV-2 Vaccine;Baden;N Engl J Med,2021
4. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine;Skowronski;N Engl J Med,2021
5. Early rate reductions of SARS-CoV-2 infection and COVID-19 in BNT162b2 vaccine recipients;Amit;Lancet,2021
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献