Author:
Jung Hae-Ni,Park Da-Hee,Choi Yeon-Jae,Kang Se-Hyeong,Cho Hee-Jung,Choi Jeong-Min,Shim Jae-Han,Zaky Ahmed A.,Abd El-Aty A. M.,Shin Ho-Chul
Abstract
The accumulation of antimicrobial residues in edible animal products and aquaculture products could pose health concerns to unsuspecting consumers. Hence, this study aimed to develop a validated method for simultaneous quantification of chloramphenicol (CAP), thiamphenicol (TAP), florfenicol (FF), and florfenicol amine (FFA) in beef, pork, chicken, shrimp, eel, and flatfish using a quick, easy, cheap, effective, rugged, and safe (QuEChERS) extraction method coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS). Primary-secondary amine (PSA) and MgSO4 were used for sample purification. The analytes were separated on a reversed-phase analytical column. The coefficients of determination for the linear matrix-matched calibration curves were ≥0.9941. Recovery rates ranged between 64.26 and 116.51% for the four analytes with relative standard deviations (RSDs) ≤ 18.05%. The calculated limits of detection (LODs) and limits of quantification (LOQs) were 0.005–3.1 and 0.02–10.4 μg/kg, respectively. The developed method was successfully applied for monitoring samples obtained from local markets in Seoul, Republic of Korea. The target residues were not detected in any tested matrix. The designed method was versatile, sensitive, and proved suitable for quantifying residues in animal-derived products.
Subject
Nutrition and Dietetics,Endocrinology, Diabetes and Metabolism,Food Science
Reference41 articles.
1. 2020
2. Biological response to stress: implications for animal welfare, Biol Anim Stress Basic Princ Implic Anim Welf;Moberg,2000
3. 2020
4. Global trends in antimicrobial resistance in animals in low-and middle-income countries;Van Boeckel;Science,2019
5. Drug residues in foods;Boison;J AOAC Int,2004
Cited by
11 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献