Author:
Correale Luca,Buzzachera Cosme Franklim,Liberali Giulia,Codrons Erwan,Mallucci Giulia,Vandoni Matteo,Montomoli Cristina,Bergamaschi Roberto
Abstract
Purpose: To test the hypothesis that combined resistance and endurance training would improve muscle strength, fatigue, depression, and quality of life in persons with MS.Methods: Twenty-seven women with MS were randomly assigned to either control (CON, n = 13) or the experimental (EXP, n = 14) group. The participants in the EXP group trained twice a week for 12 weeks, followed by 12 weeks of detraining. Both CON and EXP groups were tested before and after 12 weeks of the intervention period, as well as 12 weeks after training cessation (follow-up), where measures of muscle strength, fatigue, depression, and quality of life were evaluated.Results: There were significant changes in maximal voluntary isometric contraction (MVIC), 1RM leg extension, and 1RM chest press following the intervention period in the EXP group (P < 0.05), but not in the CON group (P > 0.05). These changes persisted after 12 weeks of detraining. Similar findings were found for fatigue, depression, and physical and mental composites of quality of life.Conclusion: These results suggest that combined exercise training, at a minimum, prevents the disease-related deterioration of muscular performance and quality of life and well-being in persons with MS.
Subject
Clinical Neurology,Neurology
Reference46 articles.
1. Early clinical predictors and progression of irreversible disability in multiple sclerosis: an amnesic process;Confavreux;Brain.,2003
2. Incidence and prevalence of multiple sclerosis in Olmsted County, Minnesota, 1985-2000;Mayr;Neurology.,2003
3. Global, regional, and national burden of neurological disorders, 1990-2016: a systematic analysis for the GBD study 2016;GBD;Lancet Neurol.,2019
4. Managing the symptoms of multiple sclerosis: a multimodal approach;Crayton;Clin Ther.,2006
5. Muscle strength and power in persons with multiple sclerosis: a systematic review and meta-analysis;Jørgensen;J Neurol Sci.,2017
Cited by
7 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献