Author:
Furia Alessandro,Licchetta Laura,Muccioli Lorenzo,Ferri Lorenzo,Mostacci Barbara,Mazzoni Stefania,Menghi Veronica,Minardi Raffaella,Tinuper Paolo,Bisulli Francesca
Abstract
Epilepsy with auditory features (EAF) is a focal epilepsy belonging to the focal epileptic syndromes with onset at variable age according to the new ILAE Classification. It is characterized by seizures with auditory aura or receptive aphasia suggesting a lateral temporal lobe involvement of the epileptic discharge. Etiological factors underlying EAF are largely unknown. In the familial cases with an autosomal dominant pattern of inheritance several genes have been involved, among which the first discovered, LGI1, was thought to be predominant. However, increasing evidence now points to a multifactorial etiology, as familial and sporadic EAF share a virtually identical electro-clinical characterization and only a few have a documented genetic etiology. Patients with EAF usually have an unremarkable neurological examination and a good response to antiseizure medications. However, it must be underscored that total remission might be lower than expected and that treatment withdrawal might lead to relapses. Thus, a proper understanding of this condition is in order for better patient treatment and counseling. Further studies are still required to further characterize the many facets of EAF.
Subject
Neurology (clinical),Neurology
Reference40 articles.
1. ILAE Classification and Definition of Epilepsy Syndromes with Onset at a Variable Age: Position Statement by the ILAE Task Force on Nosology and Definitions. Currently in Review by the ILAE
RineyK
BogaczA
SomervilleE
HirschE
NabboutR
SchefferIE
2. On epilepsy, in its relation to ear-disease;Ormerod;Brain.,1883
3. Auditory verbal hallucinations of epileptic origin;Serino;Epilepsy Behav.,2014
4. The “voices” of joan of arc and epilepsy with auditory features;d'Orsi;Epilepsy Behav.,2016
5. Dostoevsky's medical history : diagnosis and dialectic;Rice;Russian Rev.,1983
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