Author:
Jin Ji,Guo Geng,Ren Yeqing,Yang Biao,Wu Yongqiang,Wang Shule,Sun Yanqi,Wang Xiaogang,Wang Yuxiao,Zheng Jianzhong
Abstract
Intracranial aneurysm is a severe cerebral disorder involving complicated risk factors and endovascular coiling is a common therapeutic selection for intracranial aneurysm. The recurrence is a clinical challenge in intracranial aneurysms after coil embolization. With this study, we provided a meta-analysis of the risk factors for the recurrence of intracranial aneurysm after coil embolization. Nine studies were included with a total of 1,270 studies that were retrieved from the database. The sample size of patients with intracranial aneurysms ranged from 241 to 3,530, and a total of 9,532 patients were included in the present meta-analysis. The intracranial aneurysms that occurred in middle cerebral artery (MCA) (OR = 1.09, 95% CI: 1.03–1.16, P = 0.0045) and posterior circulation (OR = 2.01, 95% CI: 1.55–2.60, P = 0.000) presented the significantly higher risk of recurrence after coil embolization. Meanwhile, intracranial aneurysms of size > 7 mm (OR = 5.38, 95%CI: 3.76–7.70, P = 0.000) had a significantly higher risk of recurrence after coil embolization. Moreover, ruptured aneurysm (OR = 2.86, 95% CI: 2.02–4.04, P = 0.000) and subarachnoid hemorrhage (SAH) (OR = 1.57, 95% CI: 1.20–2.06, P = 0.001) was positively correlated with the risk of recurrence after coil embolization. In conclusion, this meta-analysis identified the characteristics of intracranial aneurysms with MCA, posterior circulation, size > 7 mm, ruptured aneurysm, and SAH as the risk factors of recurrence after coil embolization for intracranial aneurysms.
Subject
Neurology (clinical),Neurology
Reference35 articles.
1. Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening;Brown RD;Lancet Neurol.,2014
2. Unruptured intracranial aneurysms: development, rupture and preventive management;Etminan;Nat Rev Neurol.,2016
3. Safety and efficacy of a new outreach distal access catheter, TACTICS, for coil embolization of unruptured intracranial aneurysms;Matsushige;Interv Neuroradiol.,2018
4. Complications of endovascular treatment for intracranial aneurysms: management and prevention;Ihn;Interv Neuroradiol.,2018
5. Aneurysm wall cellularity affects healing after coil embolization: assessment in a rat saccular aneurysm model;Nevzati;J Neurointerv Surg.,2020