Author:
Yang Xia,Liu Qiong,Lai Ming-feng,Ma Xiao-hong,Hao Xiao-ting,Xu Jia-jun,Guo Wan-jun
Abstract
ObjectiveMetabotropic glutamate receptor 5 (mGluR5) encephalitis is such a rare type of autoimmune encephalitis that its diagnosis remains a challenge.Case reportA 19-year-old female patient initially presented with anxiety and orthostatic leg tremors without cortical dysfunction. We found that this patient was positive for mGluR5 antibodies in both serum (1:1,000) and cerebrospinal fluid (1:32). After comprehensive intervention, the patient showed complete recovery at the 18-month follow-up.DiscussionThis report expands our knowledge of the possible presentations of mGluR5 encephalitis for early diagnosis, which makes it possible to prevent serious consequences and improve the prognosis.
Subject
Neurology (clinical),Neurology