Author:
Drane Daniel L.,Pedersen Nigel P.,Sabsevitz David S.,Block Cady,Dickey Adam S.,Alwaki Abdulrahman,Kheder Ammar
Abstract
Mapping of cortical functions is critical for the best clinical care of patients undergoing epilepsy and tumor surgery, but also to better understand human brain function and connectivity. The purpose of this review is to explore existing and potential means of mapping higher cortical functions, including stimulation mapping, passive mapping, and connectivity analyses. We examine the history of mapping, differences between subdural and stereoelectroencephalographic approaches, and some risks and safety aspects, before examining different types of functional mapping. Much of this review explores the prospects for new mapping approaches to better understand other components of language, memory, spatial skills, executive, and socio-emotional functions. We also touch on brain-machine interfaces, philosophical aspects of aligning tasks to brain circuits, and the study of consciousness. We end by discussing multi-modal testing and virtual reality approaches to mapping higher cortical functions.
Funder
National Institutes of Health
Medtronic
Citizens United for Research in Epilepsy
Subject
Clinical Neurology,Neurology
Cited by
15 articles.
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