Neuroprotective Effects of Fingolimod Supplement on the Retina and Optic Nerve in the Mouse Model of Experimental Autoimmune Encephalomyelitis-Reference-Cited by-同舟云学术

Neuroprotective Effects of Fingolimod Supplement on the Retina and Optic Nerve in the Mouse Model of Experimental Autoimmune Encephalomyelitis

Published:2021-04-26 Issue: Volume:15 Page:
ISSN:1662-453X
Container-title:Frontiers in Neuroscience
language:
Short-container-title:Front. Neurosci.

Author:

Yang Tao,Zha Zheng,Yang Xiao,Kang YueZhi,Wang Xin,Tong Yanping,Zhao XueSong,Wang Lei,Fan YongPing

Abstract

Graphical AbstractOur results show that fingolimod is a potential therapeutic approach to prevent EAE-induced visual impairment. Moreover, we show that the observed neuro-ophthalmological protective effects of fingolimod were dependent on hampering hyper-gliosis in the retina and optic nerve.

Publisher

Frontiers Media SA

Subject

General Neuroscience

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