Recognition of regions of stroke injury using multi-modal frequency features of electroencephalogram

Abstract

ObjectiveNowadays, increasingly studies are attempting to analyze strokes in advance. The identification of brain damage areas is essential for stroke rehabilitation.ApproachWe proposed Electroencephalogram (EEG) multi-modal frequency features to classify the regions of stroke injury. The EEG signals were obtained from stroke patients and healthy subjects, who were divided into right-sided brain injury group, left-sided brain injury group, bilateral brain injury group, and healthy controls. First, the wavelet packet transform was used to perform a time-frequency analysis of the EEG signal and extracted a set of features (denoted as WPT features). Then, to explore the nonlinear phase coupling information of the EEG signal, phase-locked values (PLV) and partial directed correlations (PDC) were extracted from the brain network, and the brain network produced a second set of features noted as functional connectivity (FC) features. Furthermore, we fused the extracted multiple features and used the resnet50 convolutional neural network to classify the fused multi-modal (WPT + FC) features.ResultsThe classification accuracy of our proposed methods was up to 99.75%.SignificanceThe proposed multi-modal frequency features can be used as a potential indicator to distinguish regions of brain injury in stroke patients, and are potentially useful for the optimization of decoding algorithms for brain-computer interfaces.