The Developing Human Connectome Project Neonatal Data Release

Author:

Edwards A. David,Rueckert Daniel,Smith Stephen M.,Abo Seada Samy,Alansary Amir,Almalbis Jennifer,Allsop Joanna,Andersson Jesper,Arichi Tomoki,Arulkumaran Sophie,Bastiani Matteo,Batalle Dafnis,Baxter Luke,Bozek Jelena,Braithwaite Eleanor,Brandon Jacqueline,Carney Olivia,Chew Andrew,Christiaens Daan,Chung Raymond,Colford Kathleen,Cordero-Grande Lucilio,Counsell Serena J.,Cullen Harriet,Cupitt John,Curtis Charles,Davidson Alice,Deprez Maria,Dillon Louise,Dimitrakopoulou Konstantina,Dimitrova Ralica,Duff Eugene,Falconer Shona,Farahibozorg Seyedeh-Rezvan,Fitzgibbon Sean P.,Gao Jianliang,Gaspar Andreia,Harper Nicholas,Harrison Sam J.,Hughes Emer J.,Hutter Jana,Jenkinson Mark,Jbabdi Saad,Jones Emily,Karolis Vyacheslav,Kyriakopoulou Vanessa,Lenz Gregor,Makropoulos Antonios,Malik Shaihan,Mason Luke,Mortari Filippo,Nosarti Chiara,Nunes Rita G.,O’Keeffe Camilla,O’Muircheartaigh Jonathan,Patel Hamel,Passerat-Palmbach Jonathan,Pietsch Maximillian,Price Anthony N.,Robinson Emma C.,Rutherford Mary A.,Schuh Andreas,Sotiropoulos Stamatios,Steinweg Johannes,Teixeira Rui Pedro Azeredo Gomes,Tenev Tencho,Tournier Jacques-Donald,Tusor Nora,Uus Alena,Vecchiato Katy,Williams Logan Z. J.,Wright Robert,Wurie Julia,Hajnal Joseph V.

Abstract

The Developing Human Connectome Project has created a large open science resource which provides researchers with data for investigating typical and atypical brain development across the perinatal period. It has collected 1228 multimodal magnetic resonance imaging (MRI) brain datasets from 1173 fetal and/or neonatal participants, together with collateral demographic, clinical, family, neurocognitive and genomic data from 1173 participants, together with collateral demographic, clinical, family, neurocognitive and genomic data. All subjects were studied in utero and/or soon after birth on a single MRI scanner using specially developed scanning sequences which included novel motion-tolerant imaging methods. Imaging data are complemented by rich demographic, clinical, neurodevelopmental, and genomic information. The project is now releasing a large set of neonatal data; fetal data will be described and released separately. This release includes scans from 783 infants of whom: 583 were healthy infants born at term; as well as preterm infants; and infants at high risk of atypical neurocognitive development. Many infants were imaged more than once to provide longitudinal data, and the total number of datasets being released is 887. We now describe the dHCP image acquisition and processing protocols, summarize the available imaging and collateral data, and provide information on how the data can be accessed.

Funder

European Research Council

Medical Research Council

Wellcome Trust

Publisher

Frontiers Media SA

Subject

General Neuroscience

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