Different topological patterns in structural covariance networks between high and low delay discounters

Author:

Jung Wi Hoon,Kim Euitae

Abstract

IntroductionPeople prefer immediate over future rewards because they discount the latter’s value (a phenomenon termed “delay discounting,” used as an index of impulsivity). However, little is known about how the preferences are implemented in brain in terms of the coordinated pattern of large-scale structural brain networks.MethodsTo examine this question, we classified high discounting group (HDG) and low discounting group (LDG) in young adults by assessing their propensity for intertemporal choice. We compared global and regional topological properties in gray matter volume-based structural covariance networks between two groups using graph theoretical analysis.ResultsHDG had less clustering coefficient and characteristic path length over the wide sparsity range than LDG, indicating low network segregation and high integration. In addition, the degree of small-worldness was more significant in HDG. Locally, HDG showed less betweenness centrality (BC) in the parahippocampal gyrus and amygdala than LDG.DiscussionThese findings suggest the involvement of structural covariance network topology on impulsive choice, measured by delay discounting, and extend our understanding of how impulsive choice is associated with brain morphological features.

Publisher

Frontiers Media SA

Subject

General Psychology

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