The Next Frontier of Regulatory T Cells: Promising Immunotherapy for Autoimmune Diseases and Organ Transplantations

Author:

Terry Lauren V.,Oo Ye Htun

Publisher

Frontiers Media SA

Subject

Immunology,Immunology and Allergy

Reference116 articles.

1. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases;Sakaguchi;J Immunol.,1995

2. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells;Liu;J Exp Med.,2006

3. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance;Itoh;J Immunol.,1999

4. Control of regulatory T cell development by the transcription factor Foxp3;Hori;Science.,2003

5. Critical evaluation of regulatory T cells in autoimmunity: are the most potent regulatory specificities being ignored?;Vandenbark;Immunology.,2008

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