The role of carcinoembryonic antigen-related cell adhesion molecule 1 in cancer-Reference-Cited by-同舟云学术

The role of carcinoembryonic antigen-related cell adhesion molecule 1 in cancer

Published:2023-11-24 Issue: Volume:14 Page:
ISSN:1664-3224
Container-title:Frontiers in Immunology
language:
Short-container-title:Front. Immunol.

Author:

Götz Lisa,Rueckschloss Uwe,Balk Gözde,Pfeiffer Verena,Ergün Süleyman,Kleefeldt Florian

Abstract

The Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), also known as CD66a, is a member of the immunoglobulin superfamily. CEACAM1 was shown to be a prognostic marker in patients suffering from cancer. In this review, we summarize pre-clinical and clinical evidence linking CEACAM1 to tumorigenicity and cancer progression. Furthermore, we discuss potential CEACAM1-based mechanisms that may affect cancer biology.

Publisher

Frontiers Media SA

Subject

Immunology,Immunology and Allergy

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