The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Randomized, Double-Blind, Placebo-Controlled, Single-Center Trial-Reference-Cited by-同舟云学术

The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI): A Randomized, Double-Blind, Placebo-Controlled, Single-Center Trial

Published:2020-09-08 Issue: Volume:11 Page:
ISSN:1664-3224
Container-title:Frontiers in Immunology
language:
Short-container-title:Front. Immunol.

Author:

Spinella Philip C.,Thomas Kimberly A.,Turnbull Isaiah R.,Fuchs Anja,Bochicchio Kelly,Schuerer Douglas,Reese Stacey,Coleoglou Centeno Adrian A.,Horn Christopher B.,Baty Jack,Shea Susan M.,Meledeo M. Adam,Pusateri Anthony E.,Levy Jerrold H.,Cap Andrew P.,Bochicchio Grant V.,

Funder

U.S. Department of Defense

Publisher

Frontiers Media SA

Subject

Immunology,Immunology and Allergy

Reference64 articles.

1. Increasing trauma deaths in the United States.;Rhee;Ann Surg.,2014

2. Prehospital hemostatic resuscitation to achieve zero preventable deaths after traumatic injury.;Spinella;Curr Opin Hematol.,2017

3. Acute traumatic coagulopathy.;Brohi;J Trauma.,2003

4. Early coagulopathy predicts mortality in trauma.;MacLeod;J Trauma.,2003

5. Early coagulopathy in multiple injury: an analysis from the german trauma registry on 8724 patients.;Maegele;Injury.,2007

Cited by 30 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Population pharmacokinetic modelling and simulation of tranexamic acid in adult trauma patients;British Journal of Clinical Pharmacology;2024-05-02

2. Dose-Dependent Tranexamic Acid Blunting of Penumbral Leukocyte Mobilization and Blood–Brain Barrier Permeability Following Traumatic Brain Injury: An In Vivo Murine Study;Neurocritical Care;2024-03-05

3. Differentiating Pathologic from Physiologic Fibrinolysis: Not as Simple as Conventional Thrombelastography;Journal of the American College of Surgeons;2024-02-01

4. Dosing of tranexamic acid in trauma;Current Opinion in Anaesthesiology;2024-01-24

5. Blood failure: traumatic hemorrhage and the interconnections between oxygen debt, endotheliopathy, and coagulopathy;Clinical and Experimental Emergency Medicine;2023-11-29