A Critical Blimp-1-Dependent IL-10 Regulatory Pathway in T Cells Protects From a Lethal Pro-inflammatory Cytokine Storm During Acute Experimental Trypanosoma brucei Infection

Author:

De Trez Carl,Stijlemans Benoit,Bockstal Viki,Cnops Jennifer,Korf Hannelie,Van Snick Jacques,Caljon Guy,Muraille Eric,Humphreys Ian R.,Boon Louis,Van Ginderachter Jo A.,Magez Stefan

Funder

Belgian Federal Science Policy Office

Fonds Wetenschappelijk Onderzoek

Vrije Universiteit Brussel

Publisher

Frontiers Media SA

Subject

Immunology,Immunology and Allergy

Reference64 articles.

1. Regulation and functions of the IL-10 family of cytokines in inflammation and disease;Ouyang;Annu Rev Immunol,2011

2. The regulation of IL-10 production by immune cells;O'Garra;Nat Rev Immunol,2010

3. Interleukin-10-deficient mice and inflammatory bowel disease associated cancer development;Sturlan;Carcinogenesis.,2001

4. In the absence of endogenous il-10, mice acutely infected with toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma, and TNF-alpha;Gazzinelli;J Immunol,1996

5. IL-10 regulates viral lung immunopathology during acute respiratory syncytial virus infection in mice;Loebbermann;PLoS ONE,2012

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