Binding of von Willebrand Factor to Complement C1q Decreases the Phagocytosis of Cholesterol Crystals and Subsequent IL-1 Secretion in Macrophages

Author:

Donat Claudia,Thanei Sophia,Trendelenburg Marten

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Frontiers Media SA

Subject

Immunology,Immunology and Allergy

Reference64 articles.

1. Complement. First of two parts;Walport;N Engl J Med,2001

2. Complement, a target for therapy in inflammatory and degenerative diseases;Morgan;Nat Rev Drug Discov,2015

3. The non-classical functions of the classical complement pathway recognition subcomponent C1q;Nayak;Immunol Lett,2010

4. Modulation of FcR function by complement: subcomponent C1q enhances the phagocytosis of IgG-opsonized targets by human monocytes and culture-derived macrophages;Bobak;J Immunol,1987

5. Complement proteins C1q and MBL are pattern recognition molecules that signal immediate and long-term protective immune functions;Bohlson;Mol Immunol,2007

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