CTLA4 Message Reflects Pathway Disruption in Monogenic Disorders and Under Therapeutic Blockade-Reference-Cited by-同舟云学术

CTLA4 Message Reflects Pathway Disruption in Monogenic Disorders and Under Therapeutic Blockade

Published:2019-05-16 Issue: Volume:10 Page:
ISSN:1664-3224
Container-title:Frontiers in Immunology
language:
Short-container-title:Front. Immunol.

Author:

Garcia-Perez Josselyn E.,Baxter Ryan M.,Kong Daniel S.,Tobin Richard,McCarter Martin,Routes John M.,Verbsky James,Jordan Michael B.,Dutmer Cullen M.,Hsieh Elena W. Y.

Funder

Foundation for the National Institutes of Health

Boettcher Foundation

Jeffrey Modell Foundation

Publisher

Frontiers Media SA

Subject

Immunology,Immunology and Allergy

Reference29 articles.

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3. Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy;Lo;Science.,2015

4. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4;Tivol;Immunity.,1995

5. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4;Waterhouse;Science.,1995

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