In Silico Workflow for the Discovery of Natural Products Activating the G Protein-Coupled Bile Acid Receptor 1
Author:
Publisher
Frontiers Media SA
Subject
General Chemistry
Reference61 articles.
1. Pharmacophore modeling and in Silico/in Vitro screening for human cytochrome P450 11B1 and cytochrome P450 11B2 inhibitors;Akram;Front. Chem.,2017
2. The TGR5 receptor mediates bile acid-induced itch and analgesia;Alemi;J. Clin. Invest.,2013
3. Bile acids: emerging role in management of liver diseases;Asgharpour;Hepatol. Int.,2015
4. Feeling nature's PAINS: natural products, natural product drugs, and pan assay interference compounds (PAINS);Baell;J. Nat. Prod.,2016
5. Release of GLP-1 and PYY in response to the activation of G protein-coupled bile acid receptor TGR5 is mediated by Epac/PLC-epsilon pathway and modulated by endogenous H2S;Bala;Front. Physiol.,2014
Cited by 19 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Mechanism of action of the bile acid receptor TGR5 in obesity;Acta Pharmaceutica Sinica B;2024-02
2. Drug Repurposing: Scopes in Herbal/Natural Products-based Drug Discovery and Role of in silico Techniques;Drug Repurposing - Advances, Scopes and Opportunities in Drug Discovery;2023-06-07
3. Application of computational methods for class A GPCR Ligand discovery;Journal of Molecular Graphics and Modelling;2023-06
4. Mind the Gap—Deciphering GPCR Pharmacology Using 3D Pharmacophores and Artificial Intelligence;Pharmaceuticals;2022-10-22
5. Therapeutic Opportunities of GPBAR1 in Cholestatic Diseases;Frontiers in Pharmacology;2022-01-13
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3