Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors-Reference-Cited by-同舟云学术

Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors

Published:2019-04-30 Issue: Volume:7 Page:
ISSN:2296-2646
Container-title:Frontiers in Chemistry
language:
Short-container-title:Front. Chem.

Author:

Gonzaga Daniel T. G.,Oliveira Felipe H.,Ranke N. L. von,Pinho G. Q.,Salles Juliana P.,Bello Murilo L.,Rodrigues Carlos R.,Castro Helena C.,Souza Hellen V. C. M. de,Reis Caroline R. C.,Leme Rennan P. P.,Mafra João C. M.,Pinheiro Luiz C. S.,Hoelz Lucas V. B.,Boechat Nubia,Faria Robson X.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Frontiers Media SA

Subject

General Chemistry

Reference80 articles.

1. GROMACS: high performance molecular simulations through multi-level parallelism from laptops to supercomputers;Abraham;SoftwareX,2015

2. p-Toluenesulfonic acid-catalyzed solvent-free synthesis and biological evaluation of new 1-(4′,6′-dimethylpyrimidin-2'-yl)-5-amino-4H-3-arylpyrazole derivatives;Aggarwal;Med. Chem. Res,2014

3. Synthesis of novel pyrazole-thiadiazole hybrid as potential potent and selective cyclooxygenase-2 (COX-2) inhibitors;Alegaon;Bioorg. Med. Chem. Lett,2014

4. Physiological roles and potential therapeutic applications of the P2X7 receptor in inflammation and pain;Alves;Molecules,2013

5. Review: biologically active pyrazole derivatives;Ansari;N. J. Chem,2017

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. In vitro evaluation of 2-(1H-pyrazol-1-yl)-1,3,4-thiadiazole derivatives against replicative and infective stages of Trypanosoma cruzi;Journal of Bioenergetics and Biomembranes;2023-11-03

2. Synthetic molecules as P2X7 receptor antagonists: A medicinal chemistry update focusing the therapy of inflammatory diseases;European Journal of Pharmacology;2023-10

3. In silico and pharmacological study of N,S-acetal juglone derivatives as inhibitors of the P2X7 receptor-promoted in vitro and in vivo inflammatory response;Biomedicine & Pharmacotherapy;2023-06

4. Thiadiazole – A promising structure in design and development of anti-Alzheimer agents;International Immunopharmacology;2023-05

5. Synthesis, Biological Evaluation and Molecular Modeling Studies of Naphthoquinone Sulfonamides and Sulfonate Ester Derivatives as P2X7 Inhibitors;Molecules;2023-01-06