Author:
Luo Wei,Wang Lixia,Chen Zhengrong,Liu Ming,Zhao Yixue,Wu Yucan,Huang Bing,Wang Ping
Abstract
E11 causes acute fulminant hepatitis in newborns. We investigated the pathological changes of different tissues from premature male twins who died due to E11 infection. The E11 expression level was higher in the liver than in other tissues. IP10 was upregulated in liver tissue in the patient group, and might be regulated by IFNAR and IRF7, whereas IFNα was regulated by IFNAR or IRF5.
Funder
Basic and Applied Basic Research Foundation of Guangdong Province