Macrophages From Subjects With Isolated GH/IGF-I Deficiency Due to a GHRH Receptor Gene Mutation Are Less Prone to Infection by Leishmania amazonensis

Author:

Barrios Mônica R.,Campos Viviane C.,Peres Nalu T. A.,de Oliveira Laís L.,Cazzaniga Rodrigo A.,Santos Márcio B.,Aires Murilo B.,Silva Ricardo L. L.,Barreto Aline,Goto Hiro,Almeida Roque P.,Salvatori Roberto,Aguiar-Oliveira Manuel H.,Jesus Amélia M. R.

Funder

Fundação de Apoio à Pesquisa e à Inovação Tecnológica do Estado de Sergipe

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Frontiers Media SA

Subject

Infectious Diseases,Microbiology (medical),Immunology,Microbiology

Reference30 articles.

1. Growth hormone deficiency: health and longevity;Aguiar-Oliveira;Endocr. Rev.,2018

2. Effect of severe growth hormone (GH) deficiency due to a mutation in the GH-releasing hormone receptor on insulin-like growth factors (IGFs), IGF-binding proteins, and ternary complex formation throughout life;Aguiar-Oliveira;J. Clin. Endocrinol. Metab.,1999

3. Longevity in untreated congenital growth hormone deficiency due to a homozygous mutation in the GHRH receptor gene;Aguiar-Oliveira;J. Clin. Endocrinol. Metab.,2010

4. Involvement of IGF-1 and Akt in M1/M2 activation state in bone marrow-derived macrophages;Barrett;Exp. Cell Res.,2015

5. Mycobacterium leprae-induced Insulin-like Growth Factor i attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages;Batista-Silva;Sci. Rep.,2016

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