Case Report: Early Breast Cancer Recurrence Mimicking BIA-ALCL in a Patient With Multiple Breast Procedures

Author:

Materazzo Marco,Vanni Gianluca,Pellicciaro Marco,Anemona Lucia,Servadei Francesca,Giacobbi Erika,Farinaccio Andrea,Pistolese Chiara Adriana,Perretta Tommaso,Chiocchi Marcello,Bruno Valentina,Tacconi Federico,Sadri Amir,De Majo Adriano,Di Pasquali Camilla,Meucci Rosaria,Santori Francesca,Cotesta Maria,Buonomo Oreste Claudio

Abstract

Breast reconstruction plays a fundamental role in the therapeutic process of breast cancer treatment and breast implants represents the leading breast reconstruction strategy. Breast Implant Associated-Anaplastic Large Cell Lymphoma (BIA-ALCL), locoregional recurrence in the skin flap, and skin flap necrosis are well-known complications following mastectomy and immediate breast reconstruction (IBR). We report a case of locoregional cancer recurrence in the mastectomy flap mimicking BIA-ALCL, in a patient who underwent 6 breast procedures in four facilities across 15 years including immediate breast reconstruction with macrotextured breast implants. Despite the rate and onset of the disease, clinicians should be aware of BIA-ALCL. Due to the risk of false negative results of fine needle aspiration, clinical suspicion of BIA-ALCL should drive clinicians' choices, aside from cytological results. In the present case, surgical capsulectomy of the abnormal periprosthesic tissue revealed locoregional recurrence.

Funder

Ministero della Salute

Publisher

Frontiers Media SA

Subject

Surgery

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