Author:
Xie Zhenliang,Li Jincheng,Huang Pu,Zhang Ye,Yang Jingkuan,Liu Kangdong,Jiang Yanan
Abstract
Gastrointestinal cancer represents a public health concern that seriously endangers human health. The emerging single-cell sequencing (SCS) technologies are different from the large-scale sequencing technologies which provide inaccurate data. SCS is a powerful tool for deciphering the single-cell resolutions of cellular and molecular landscapes, revealing the features of single-cell genomes, transcriptomes, and epigenomes. Recently, SCS has been applied in the field of gastrointestinal cancer research for clarifying the origin and heterogeneity of gastrointestinal cancer, acquiring micro-environmental information, and improving diagnostic and treatment methods. This review outlines the applications of SCS in gastrointestinal cancer research and summarizes the most recent advances in the field.
Funder
National Natural Science Foundation of China
National Youth Science Foundation
Youth and Middle-aged Scientific and Technological Innovation Leading Talents Program of the Corps
Henan Province Science and Technology Innovation Talent Program
Cited by
2 articles.
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