Tox21Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways as Mediated by Exposure to Environmental Chemicals and Drugs-Reference-Cited by-同舟云学术

Tox21Challenge to Build Predictive Models of Nuclear Receptor and Stress Response Pathways as Mediated by Exposure to Environmental Chemicals and Drugs

Published:2016-01-14 Issue: Volume:3 Page:
ISSN:2296-665X
Container-title:Frontiers in Environmental Science
language:
Short-container-title:Front. Environ. Sci.

Author:

Huang Ruili,Xia Menghang,Nguyen Dac-Trung,Zhao Tongan,Sakamuru Srilatha,Zhao Jinghua,Shahane Sampada A.,Rossoshek Anna,Simeonov Anton

Funder

National Institutes of Health

U.S. Environmental Protection Agency

National Center for Advancing Translational Sciences

Publisher

Frontiers Media SA

Subject

General Environmental Science

Reference39 articles.

1. An introduction to kernel and nearest-neighbor nonparametric regression;Altman;Am. Stat.,1992

2. Profiling of the Tox21 chemical collection for mitochondrial function to identify compounds that acutely decrease mitochondrial membrane potential;Attene-Ramos;Environ. Health Perspect.,2015

3. A method for multiconformational modeling of the three-dimensional shape of a molecule;Bartashevich;J. Struct. Chem.,2002

4. Random forests;Breiman;Mach. Learn.,2001

5. Cell-based high-throughput screening for aromatase inhibitors in the Tox21 10K library;Chen;Toxicol. Sci.,2015

Cited by 122 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The role of artificial intelligence in the development of anticancer therapeutics from natural polyphenols: Current advances and future prospects;Pharmacological Research;2024-10

2. The changing scenario of drug discovery using AI to deep learning: Recent advancement, success stories, collaborations, and challenges;Molecular Therapy - Nucleic Acids;2024-09

3. Insilico toxicity prediction by using ProTox-II computational tools;Asia-Pacific Journal of Pharmacotherapy & Toxicology;2024-08-29

4. Semisupervised Learning to Boost hERG, Nav1.5, and Cav1.2 Cardiac Ion Channel Toxicity Prediction by Mining a Large Unlabeled Small Molecule Data Set;Journal of Chemical Information and Modeling;2024-08-07

5. Machine Learning Prediction of On/Off Target-driven Clinical Adverse Events;Pharmaceutical Research;2024-08