Author:
Wu Lei,Yang Bincai,Yuan Xu,Hong Jinxuan,Peng Min,Chen Ji-Long,Song Zhongbao
Abstract
African swine fever (ASF) is an acute lethal hemorrhagic viral disease in domestic pigs and wild boars; is widely epidemic in Africa, Europe, Asia, and Latin America; and poses a huge threat to the pig industry worldwide. ASF is caused by the infection of the ASF virus (ASFV), a cytoplasmic double-stranded DNA virus belonging to the Asfarviridae family. Here, we review how the virus regulates the host immune response and its mechanisms at different levels, including interferon modulation, inflammation, apoptosis, antigen presentation, and cellular immunity.
Funder
Natural Science Foundation of Fujian Province
Subject
Microbiology (medical),Microbiology
Cited by
7 articles.
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