Model-driven discovery of synergistic inhibitors against E. coli and S. enterica serovar Typhimurium targeting a novel synthetic lethal pair, aldA and prpC

Author:

Aziz Ramy K.,Khaw Valerie L.,Monk Jonathan M.,Brunk Elizabeth,Lewis Robert,Loh Suh I.,Mishra Arti,Nagle Amrita A.,Satyanarayana Chitkala,Dhakshinamoorthy Saravanakumar,Luche Michele,Kitchen Douglas B.,Andrews Kathleen A.,Palsson Bernhard Ø.,Charusanti Pep

Funder

NIH/NIGMS

Publisher

Frontiers Media SA

Subject

Microbiology (medical),Microbiology

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4. Involvement of lactaldehyde dehydrogenase in several metabolic pathways of Escherichia coli K12.;Baldoma;J. Biol. Chem.,1987

5. Robust Salmonella metabolism limits possibilities for new antimicrobials.;Becker;Nature,2006

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