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A Middle-Out Modeling Strategy to Extend a Colon Cancer Logical Model Improves Drug Synergy Predictions in Epithelial-Derived Cancer Cell Lines

  • Published:2020-10-09 Issue: Volume:7 Page:
  • ISSN:2296-889X
  • Container-title:Frontiers in Molecular Biosciences
  • language:
  • Short-container-title:Front. Mol. Biosci.

Author:

Tsirvouli Eirini,Touré Vasundra,Niederdorfer Barbara,Vázquez Miguel,Flobak Åsmund,Kuiper Martin

Publisher

Frontiers Media SA

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Molecular Biology,Biochemistry

Reference117 articles.

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2. Combinatorial drug therapy for cancer in the post-genomic era.;Al-Lazikani;Nat. Biotechnol.,2012

3. Network-based inference of protein activity helps functionalize the genetic landscape of cancer.;Alvarez;Nat. Genet.,2016

4. Computational models for predicting drug responses in cancer research.;Azuaje;Brief. Bioinform.,2017

5. Predictive mathematical models of cancer signalling pathways.;Bachmann;J. Intern. Med.,2012

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