Dexmedetomidine Protects Mouse Brain from Ischemia-Reperfusion Injury via Inhibiting Neuronal Autophagy through Up-Regulating HIF-1α-Reference-Cited by-同舟云学术

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Dexmedetomidine Protects Mouse Brain from Ischemia-Reperfusion Injury via Inhibiting Neuronal Autophagy through Up-Regulating HIF-1α

Published:2017-07-06 Issue: Volume:11 Page:
ISSN:1662-5102
Container-title:Frontiers in Cellular Neuroscience
language:
Short-container-title:Front. Cell. Neurosci.

Author:

Luo Cong,Ouyang Ming-Wen,Fang Ying-Ying,Li Shu-Ji,Zhou Quan,Fan Jun,Qin Zai-Sheng,Tao Tao

Funder

National Natural Science Foundation of China

Publisher

Frontiers Media SA

Subject

Cellular and Molecular Neuroscience

Reference53 articles.

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2. Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains;Bellot;Mol. Cell. Biol.,2009

3. Molecular targets and mechanism of action of dexmedetomidine in treatment of ischemia/reperfusion injury;Cai;Mol. Med. Rep.,2014

4. Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia;Carloni;Autophagy,2010

5. Blockade of apoptosis signal-regulating kinase 1 attenuates matrix metalloproteinase 9 activity in brain endothelial cells and the subsequent apoptosis in neurons after ischemic injury;Cheon;Front. Cell. Neurosci.,2016

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1. Dexmedetomidine directly binds to and inhibits Toll-like receptor 4;International Immunopharmacology;2024-11

2. Dexmedetomidine alleviates blood-brain barrier disruption in rats after cerebral ischemia-reperfusion by suppressing JNK and p38 MAPK signaling;The Korean Journal of Physiology & Pharmacology;2024-05-01

3. Targeting PI3K/Akt in Cerebral Ischemia Reperfusion Injury Alleviation: From Signaling Networks to Targeted Therapy;Molecular Neurobiology;2024-03-05

4. Effect of Postoperative Prolonged sedation with Dexmedetomidine after successful reperfusion with Endovascular Thrombectomy on long-term prognosis in patients with acute ischemic stroke (PPDET): study protocol for a randomized controlled trial;Trials;2024-03-04

5. The Dual Role of Autophagy in Postischemic Brain Neurodegeneration of Alzheimer’s Disease Proteinopathy;International Journal of Molecular Sciences;2023-09-07

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