Selective Modulation of α5 GABAA Receptors Exacerbates Aberrant Inhibition at Key Hippocampal Neuronal Circuits in APP Mouse Model of Alzheimer’s Disease-Reference-Cited by-同舟云学术

Selective Modulation of α5 GABAA Receptors Exacerbates Aberrant Inhibition at Key Hippocampal Neuronal Circuits in APP Mouse Model of Alzheimer’s Disease

Published:2020-11-11 Issue: Volume:14 Page:
ISSN:1662-5102
Container-title:Frontiers in Cellular Neuroscience
language:
Short-container-title:Front. Cell. Neurosci.

Author:

Petrache Alexandra L.,Khan Archie A.,Nicholson Martin W.,Monaco Alessandra,Kuta-Siejkowska Martyna,Haider Shozeb,Hilton Stephen,Jovanovic Jasmina N.,Ali Afia B.

Funder

Medical Research Council

Mauritius Research Council

Publisher

Frontiers Media SA

Subject

Cellular and Molecular Neuroscience

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4. Native γ-aminobutyric acid type A receptors from rat hippocampus, containing both α1 and α5 subunits, exhibit a single benzodiazepine binding site with α5 pharmacological properties;Araujo;J. Pharmacol. Exp. Ther.,1999

5. Preclinical and clinical pharmacology of the GABAA receptor α5 subtype-selective inverse agonist α5IA;Atack;Pharmacol. Ther.,2010

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