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Immune Factor, TNFα, Disrupts Human Brain Organoid Development Similar to Schizophrenia—Schizophrenia Increases Developmental Vulnerability to TNFα

  • Published:2020-08-28 Issue: Volume:14 Page:
  • ISSN:1662-5102
  • Container-title:Frontiers in Cellular Neuroscience
  • language:
  • Short-container-title:Front. Cell. Neurosci.

Author:

Benson Courtney A.,Powell Hana R.,Liput Michal,Dinham Siddhartha,Freedman David A.,Ignatowski Tracey A.,Stachowiak Ewa K.,Stachowiak Michal K.

Funder

National Science Foundation

New York State Department of Health

Publisher

Frontiers Media SA

Subject

Cellular and Molecular Neuroscience

Reference51 articles.

1. Serum TNF-α, IL-10 and IL-2 in schizophrenic patients before and after treatment with risperidone and clozapine;Ajami;Iran. J. Immunol.,2014

2. Calretinin immunoreactivity in focal cortical dysplasias and in non-malformed epileptic cortex;Barinka;Epilepsy Res.,2010

3. Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia;Brennand;Mol. Psychiatry,2015

4. Maternal cytokine levels during pregnancy and adult psychosis;Buka;Brain Behav. Immun.,2001

5. Prenatal infection, maternal immune activation, and risk for schizophrenia;Canetta;Transl. Neurosci.,2012
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