Influence of artefacts generated by titanium and zirconium implants in the study of trabecular bone architecture in cone-beam CT images

Abstract

Objectives: To evaluate the influence of artefacts generated by titanium and zirconium implants on trabecular bone architecture assessment through cone-beam CT (CBCT). The influence of kilovoltage (kVp) and metal artefact reduction (MAR) in such analysis was also assessed. Methods: CBCT scans were obtained with Picasso Trio with or without a titanium or zirconium implants in a posterior region of a mandible using 70, 80 or 90 kVp, with or without MAR. The other acquisition settings were constant: field of view 8 × 5 cm, voxel size 0.2 mm, 5 mA, 24 s and 720 frames. Two volumes of interest (VOIs) were determined comprising trabecular bone mesial and distal to the implant area. The following morphometric parameters were measured: connectivity density (Conn. Dn.), fractal dimension (FD), bone volume fraction (BV/TV), bone surface density (BS/TV), trabecular thickness (Tb. Th.), and trabecular spacing (Tb. Sp.), and compared by multiway ANOVA (α = 0.05). Results: For Conn. Dn. and FD, with MAR, the zirconium group showed values significantly lower than the other groups (p < 0.05). For BV/TV, BS/TV, Tb. Th. and Tb. Sp., the zirconium group showed the highest values, regardless of MAR condition (p < 0.05). MAR increased BS/TV and Tb. Th. values, and decreased FD values for zirconium group. In general, the kVp level did not influence trabecular morphometric parameters. Conclusion: The assessment of the trabecular bone architecture was mainly influenced by the expression of the artefacts generated by zirconium implants. MAR decreased the FD and increased the BS/TV and Tb.Th. values regardless of the kVp level.