Developments in functional imaging of the placenta

Author:

Clark Alys1,Flouri Dimitra23,Mufti Nada34,James Joanna5,Clements Eleanor3,Aughwane Rosalind4,Aertsen Michael6,David Anna4,Melbourne Andrew23ORCID

Affiliation:

1. Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand

2. Medical Physics and Biomedical Engineering, University College London, London, UK

3. School of Biomedical Engineering and Imaging Sciences, King’s College London, London, UK

4. Elizabeth Garrett Anderson Institute for Women’s Health, University College London, London, UK

5. Department of Obstetrics and Gynaecology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand

6. Department of Radiology, University Hospitals KU Leuven, Leuven, Belgium

Abstract

The placenta is both the literal and metaphorical black box of pregnancy. Measurement of the function of the placenta has the potential to enhance our understanding of this enigmatic organ and serve to support obstetric decision making. Advanced imaging techniques are key to support these measurements. This review summarises emerging imaging technology being used to measure the function of the placenta and new developments in the computational analysis of these data. We address three important examples where functional imaging is supporting our understanding of these conditions: fetal growth restriction, placenta accreta, and twin-twin transfusion syndrome.

Publisher

British Institute of Radiology

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

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